Anti-Aging· IV / Injection
NAD+ IV
- IV therapy
- Off-label
NAD+ IV therapy delivers nicotinamide adenine dinucleotide — a coenzyme central to cellular energy production and DNA repair — directly to the bloodstream. Used off-label for energy, cognitive clarity, and recovery.
Typically used for:
Supporting mitochondrial function, cognitive sharpness, and recovery.
Benefits
What NAD+ IV can do for you.
Cellular energy
Many men report improvements in energy and mental sharpness within 1–3 sessions.
Cognitive clarity
NAD+ is central to cellular energy production; replenishing levels supports cognitive function and recovery.
Recovery support
Often used post-illness, post-travel, or during high-output training blocks.
NAD+ IV therapy infuses nicotinamide adenine dinucleotide directly into the bloodstream, bypassing oral absorption limits. The premise: NAD+ is a critical coenzyme that declines with age and is consumed by cellular stress, and replenishing it may support mitochondrial function, DNA repair, and metabolic health. The premise is biologically plausible. The clinical-evidence base is still developing.
How it works
NAD+ is a substrate for sirtuins, PARPs, and CD38 — enzymes involved in DNA repair, gene regulation, and immune function — and it is the obligate electron carrier for mitochondrial ATP production.1 Tissue NAD+ levels decline with age and chronic stress.2 Direct IV infusion raises serum levels acutely; cellular uptake depends on tissue transporters and remains an area of active research.3
What the evidence supports — and does not
Most clinical data come from observational case series and small open-label trials. Patient-reported benefits include improved energy, mental clarity, and subjective wellbeing.2 Rigorous placebo-controlled trials of IV NAD+ for general wellness indications are sparse. NAD+ precursors (NMN, NR) have somewhat more controlled-trial data, though again largely as small short-duration studies.3 Be honest about what the evidence does and does not show.
Who it is for
Healthy adults seeking energy/cognitive support, recovery from intensive training, or alongside other longevity protocols. Not appropriate during acute illness, not a treatment for any FDA-approved medical indication, and not a replacement for sleep, nutrition, or exercise. Discuss with your physician — particularly regarding interactions with cardiovascular medications.
What to expect
- 60–180 minute IV infusion depending on dose and tolerability.
- Common acute side effects: chest pressure, nausea, flushing, headache. Mitigated by slowing the infusion rate.
- Acute effects same-day; cumulative effects, where present, develop over a series of treatments.
- Typical protocols: 250–1000 mg per session, weekly to monthly.
How it works
From consult to follow-up.
Initial consultation
A board-certified physician reviews your symptoms, history, and goals. At many participating clinics the first visit is complimentary.
Baseline labs
Bloodwork tailored to the protocol. Results come back in days, not weeks. We don't prescribe before we have your numbers.
Personalized protocol
Your physician calibrates your dose based on your labs and your goals — not a template. Adjustments happen as your data evolves.
Ongoing follow-up
Recheck visits at six and twelve weeks, then quarterly. Real follow-up, structured into the plan.
- Duration
- 60–180 minute IV infusion
- Results timeline
- Acute effects same-day; cumulative effects over a series of treatments
Designed around your schedule
Consults are short
Initial visits are typically 45–60 minutes. Many participating clinics waive the fee for new patients.
Telehealth follow-ups
Where state regulations allow, follow-up visits are conducted via telehealth — no extra drive time.
Medication shipped
Prescriptions ship directly from a 503B-licensed pharmacy to your door. No standing in line.
Quarterly check-ins
Real follow-up at six and twelve weeks, then quarterly. Not constant visits, not zero visits.
Network providers
34 certified physicians offer NAD+ IV.
Every provider in the network is board-certified and credentialed.
Brandon Crandall, NP
Men's Health / Erectile Dysfunction · Syracuse, NY
Candace Remington, NP
Men's Health / Erectile Dysfunction · Tampa, FL
Deb Gross, NP
Men's Health / Erectile Dysfunction · Centralia, WA
Dr. Adriana Rosales, MD
Men's Health / Erectile Dysfunction · Seattle, WA
Dr. Aleix Bazzi, MD
Men's Health / Erectile Dysfunction · Beverly Hills, CA
Dr. Amit Grover, MD
Men's Health / Erectile Dysfunction · Seattle, WA
Dr. Ashish Bhavsar, MD
Men's Health / Erectile Dysfunction · Orange County, CA
Dr. Bona Lee, MD
Men's Health / Erectile Dysfunction · Dallas, TX
Dr. Brad Sellers, DO
Men's Health / Erectile Dysfunction · Dallas, TX
Patient reviews — NAD+ IV
★★★★☆4.0from 1 review
Lou D.
★★★★☆Omaha, NE · Dec 2024
NAD IV protocol over six weeks. Energy felt better by session three. Honest pricing, professional setting, no pressure to add other services.
Source: Internal Sample · Verified
Where to get it
Available in 23 cities.
Pick your metro to see the local clinics, providers, and booking options.
- Beverly Hills, CA2 clinics2 providers
- Dallas, TX2 clinics4 providers
- New York, NY2 clinics2 providers
- Orange County, CA2 clinics2 providers
- Syracuse, NY2 clinics2 providers
- Tampa, FL2 clinics3 providers
- Albany, NY1 clinic1 provider
- Albuquerque, NM1 clinic1 provider
- Boca Raton, FL1 clinic2 providers
- Burlington, ON1 clinic1 provider
- Centralia, WA1 clinic1 provider
- Cleveland, OH1 clinic1 provider
What sets us apart
Real physicians. Real labs. Real follow-up.
GentsMed is a network of board-certified physicians held to a single clinical standard — built to replace the cash-pay men's-health mills with actual medicine.
- Board-certified physicians.
- Every provider is licensed, NPI-verified, and credentialed by the GentsMed or Urosculpt certification board — no nurse-only prescribers, no offshore consults.
- A single clinical standard.
- Whether you see a urologist in Tampa or a dermatologist in New York, the protocol meets the same criteria.
- Labs-driven, not guess-driven.
- No prescriptions without baseline labs. No cookie-cutter dosing. Quarterly bloodwork is built into the plan.
- Real follow-up.
- Not a 'set it and forget it' Rx mill. Every protocol includes structured follow-up at 6 and 12 weeks, then quarterly.
- Transparent pricing.
- Starting-from prices where we have them, honest "consult for pricing" where we don't. No surprise bills.
- Your records stay with your physician.
- GentsMed is the network. We do not store your PHI. Your clinical data lives with your treating physician, where it belongs.
Frequently asked questions
References
- Imai S, Guarente L. NAD+ and sirtuins in aging and disease. Trends Cell Biol. 2014;24(8):464–471.(PubMed)
- Yoshino J, et al. NAD+ Intermediates: The Biology and Therapeutic Potential. Cell Metab. 2018;27(3):513–528.(PubMed)
- Conlon N, Ford D. A systems approach for evaluating bioavailability of NAD+ precursors. Adv Nutr. 2023;14(5):1100–1116.(PubMed)
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Get started
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